About SR One
SR One is a venture capital firm founded in 1985. It is primarily based out of Redwood City, United States. As of Dec 2024, SR One is an active investor, having invested in 127 companies, with 4 new investments in the last 12 months. It primarily invests in Series B round in United States based startups. Its investments are spread across a wide range of sectors from Life Sciences to High Tech and HealthTech. Most recently it led the $42M Series B round of Nomic along with Amplitude. This round also saw participation from Lux Capital and other investors.
Overall, SR One portfolio has seen 22 IPOs and 53 acquisitions including key companies like Progyny, Alere and Spero Therapeutics. A lot of funds co-invest with SR One, with names like Novo Holdings sharing a substantial percentage of its portfolio.
SR One has team of 33 people including 7 partners.
Key Metrics
Team Members
, &
Portfolio Count
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Series A, Series B &
Portfolio IPOs
Portfolio Acquisitions
Portfolio Soonicorns
Deals in last 12 months
SR One's Year-on-Year Investment Trends
SR One has invested in 127 companies over the last 33 years, with an average of 4 new investments annually in the last 10 years. In 2024, it made 8 investments. Its most recent first time investment was in Antag Therapeutics and most recent follow-on round was in Nomic.
Year | No. of Investments | ||
---|---|---|---|
1stÌý¸é´Ç³Ü²Ô»å | Follow-on | Total | |
2025 (YTD) | 0 | 0 | 0 |
2024 | 5 | 3 | 8 |
2023 | 2 | 4 | 6 |
2022 | 4 | 4 | 8 |
2021 | 4 | 4 | 8 |
2020 | 6 | 4 | 10 |
2019 | 3 | 0 | 3 |
2018 | 2 | 6 | 8 |
2017 | 5 | 7 | 12 |
2016 | 4 | 3 | 7 |

Get SR One's portfolio delivered to your inbox!
SR One's Investment Trends by Stage
SR One has made 40 investments in Series A stage with an average round size of $36.6M, 35 investments in Series B stage with an average round size of $33.5M and 16 investments in Series C stage with an average round size of $78M.Note: We have considered here, only first round of investments
Stage of entry | No. of Investments |
---|---|
Series A | 40 |
Series B | 35 |
Series C | 16 |
Series D | 8 |
Seed | 4 |
Others | 2 |
SR One's Investment Trends by Sector
SR One has a diverse portfolio, with companies operating in the Life Sciences, High Tech, HealthTech, Healthcare and Sustainability Tech. Notably, it has invested in 107 Tech companies, 84 Enterprise (B2B) companies, 8 Software companies and at least 6 companies focusing on Consumer (B2C).
Note: We have considered here, only first round of investments
Sector | No. of Investments |
---|---|
Life Sciences | 88 |
High Tech | 18 |
HealthTech | 11 |
Healthcare | 11 |
Sustainability Tech | 11 |
Others | 13 |
SR One's Investment Trends by Geography
SR One has made most investments in United States (91), followed by United Kingdom where it has made 17 investments.
Note: We have considered here, only first round of investments
Country | No. of Investments |
---|---|
United States | 74 |
United Kingdom | 14 |
Israel | 4 |
Switzerland | 3 |
Canada | 2 |
Others | 9 |
SR One's recent investments
Here are the most recent investments by SR One:
Date | Company | Location | Round Details | Round Amount | Co-Investors |
---|---|---|---|---|---|
Dec 04, 2024 | Denmark | Series A | $84.1M | Versant Ventures [+5] | |
Sep 17, 2024 | Canada | Series B | $42M | Amplitude [+3] | |
Aug 08, 2024 | United States | Series C | $112M | Novo Holdings [+4] | |
Jul 17, 2024 | Japan | Series A | $38.2M | Catalys Pacific [+4] | |
Jul 16, 2024 | Switzerland | Series C | $100M | Novo Holdings [+6] |
IPOs and Publicly Listed companies in SR One's Portfolio
Here are SR One's portfolio companies that went public:
Company | IPO Date | First Invested on | First Round of Investment | Round Size |
---|---|---|---|---|
Sep 13, 2024 | May 03, 2024 | Series C | $200M | |
Jun 28, 2024 | Mar 07, 2024 | Series C | $259M | |
Feb 10, 2023 | Jun 01, 2022 | Series B | $118M | |
Sep 15, 2022 | Aug 31, 2021 | Series D | $55M | |
Feb 04, 2022 | Oct 03, 2019 | Series B | $85M |
Acquired companies in SR One's Portfolio
Here are SR One's portfolio companies that got acquired most recently:
Company | Acquisition Date | First Invested on | First Round of Investment | Round Size |
---|---|---|---|---|
Jul 08, 2024 | Jun 30, 2016 | Series A | $51.5M | |
Aug 21, 2023 | Mar 25, 2014 | Series B | $15M | |
Aug 10, 2023 | Jan 13, 2017 | Series B | $32.3M | |
Jan 19, 2023 | - | - | - | |
Oct 24, 2022 | Nov 15, 2012 | Series B | $37.5M |
Team profile of SR One
SR One has a team of 33 membersÌýincluding 7 Partners, 11 Venture Partners and 5 PrincipalsÌýlocated in United States, United Kingdom and . SR One's team sits on the board of 1 company.Here is a list of top team members in SR One:
Name | Designation | Location | Board Memberships | Contact details |
---|---|---|---|---|
Partner | San Francisco | - | ||
Partner | London | - | ||
Partner | San Mateo | - | ||
Partner | Los Altos | - | - | |
Partner | San Francisco | - | ||
Partner | London | - | ||
Partner | United States | - | ||
Venture Partner | Switzerland | - | - | |
Venture Partner | San Francisco | - | ||
Venture Partner | London | - | ||
Venture Partner | San Francisco | - | - |
Co-investors of SR One
Over the past 33 years, 644 investors have co-invested in SR One's portfolio companies.
- Invested before SR One:ÌýAtlas Venture, Novo Holdings and 144 others have invested in rounds before SR One. There are 5 companies where Atlas Venture has invested before SR One and 5 companies where Novo Holdings has invested before SR One.
- Top Co-investors of SR One:Ìý248 investors entered a company along with SR One. These include investors like Novo Holdings (8 companies).
- Invested after SR One:ÌýA total of 250 investors have invested in SR One's portfolio after their investments. Top Investors include Orbimed (7 companies), RA Capital Management (6 companies) and Google Ventures (4 companies).

Get full list of SR One's co-investors delivered to your inbox!
Recent News related to SR One
•
FinSMEs•Jan 13, 2025•, Pivotal Life Sciences, Quan Capital, Qiming Venture Partners and 8 others
•
•
•
Fierce Biotech•Dec 04, 2024•Novo Holdings, Antag Therapeutics, Versant Ventures, Long View Ventures and 5 others
•
Business Wire•Nov 18, 2024•Avenzo Therapeutics, VelaVigo, Orbimed, Foresite Capital and 13 others
•
Contract Pharma•Oct 31, 2024•Elektrofi, Novo Holdings, RA Capital Management, Royalty Pharma and 3 others
•
•
•
Renalys raises $37.8M to take Travere's kidney disease drug into Phase 3 trial in JapanEndPoints News•Jul 17, 2024•Renalys, Catalys Pacific, SR One, JP Investment and 1 other
•