About Third Rock Ventures
Third Rock Ventures is a venture capital firm founded in 2007. It is primarily based out of Boston, United States. As of Dec 2024, Third Rock Ventures is an active investor, having invested in 70 companies, with 1 new investment in the last 12 months. It primarily invests in Series A round in United States based startups. Its investments are spread across a wide range of sectors from Life Sciences to High Tech and HealthTech. Most recently it led the $150M Series A round of Clasp Therapeutics along with Vivo Capital. This round also saw participation from Alexandria and other investors.
Overall, Third Rock Ventures portfolio has seen 22 IPOs and 19 acquisitions including key companies like Revolution Medicines, Rhythm Pharmaceuticals and Blueprint Medicines. A lot of funds co-invest with Third Rock Ventures, with names like Casdin Capital sharing a substantial percentage of its portfolio.
Third Rock Ventures has team of 94 people including 27 partners.
Key Metrics
Team Members
, &
Portfolio Count
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Series A, Series B &
Portfolio IPOs
Portfolio Acquisitions
Portfolio Soonicorns
Deals in last 12 months
Third Rock Ventures' Year-on-Year Investment Trends
Third Rock Ventures has invested in 70 companies over the last 17 years, with an average of 3 new investments annually in the last 10 years. In 2024, it made 6 investments. Its most recent first time investment was in Candid Therapeutics and most recent follow-on round was in Maze Therapeutics.
Year | No. of Investments | ||
---|---|---|---|
1stÌý¸é´Ç³Ü²Ô»å | Follow-on | Total | |
2025 (YTD) | 0 | 0 | 0 |
2024 | 3 | 3 | 6 |
2023 | 4 | 3 | 7 |
2022 | 2 | 3 | 5 |
2021 | 3 | 4 | 7 |
2020 | 4 | 4 | 8 |
2019 | 4 | 2 | 6 |
2018 | 4 | 3 | 7 |
2017 | 3 | 4 | 7 |
2016 | 5 | 1 | 6 |

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Third Rock Ventures' Investment Trends by Stage
Third Rock Ventures has made 55 investments in Series A stage, 7 investments in Series B stage, 3 investments in Series C stage and 1 investment in Series D stage.Third Rock Ventures' Investment Trends by Sector
Third Rock Ventures has a diverse portfolio, with companies operating in the Life Sciences, High Tech, HealthTech, Healthcare and Enterprise Applications. Notably, it has invested in 68 Tech companies, 60 Enterprise (B2B) companies, 3 Tech hardware companies and at least 2 companies focusing on Software.
Note: We have considered here, only first round of investments
Sector | No. of Investments |
---|---|
Life Sciences | 64 |
High Tech | 18 |
HealthTech | 4 |
Healthcare | 3 |
Enterprise Applications | 2 |
Others | 5 |
Third Rock Ventures' Investment Trends by Geography
Third Rock Ventures has made most investments in United States (69), followed by Germany where it has made 1 investments.
Third Rock Ventures' recent investments
Here are the most recent investments by Third Rock Ventures:
Date | Company | Location | Round Details | Round Amount | Co-Investors |
---|---|---|---|---|---|
Dec 04, 2024 | United States | Series D | $115M | Deep Track Capital [+13] | |
Oct 18, 2024 | United States | Series B | $225M | General Atlantic [+6] | |
Aug 19, 2024 | United States | Series D | $370M | Venrock [+17] | |
Apr 09, 2024 | United States | Series A | $100M | ||
Apr 03, 2024 | United States | Series C | $55M |
IPOs and Publicly Listed companies in Third Rock Ventures' Portfolio
Here are Third Rock Ventures' portfolio companies that went public:
Company | IPO Date | First Invested on | First Round of Investment | Round Size |
---|---|---|---|---|
Jan 31, 2025 | Mar 01, 2019 | Series C | $191M | |
Oct 25, 2024 | Jan 27, 2022 | Series A | $100M | |
Jun 07, 2024 | Mar 07, 2023 | Series A | $100M | |
Nov 10, 2023 | Feb 09, 2023 | Series A | $200M | |
Sep 04, 2020 | Mar 30, 2017 | Series A | $55M |
Acquired companies in Third Rock Ventures' Portfolio
Here are Third Rock Ventures' portfolio companies that got acquired most recently:
Company | Acquisition Date | First Invested on | First Round of Investment | Round Size |
---|---|---|---|---|
Feb 21, 2025 | Mar 12, 2010 | Series B | $37.5M | |
Jun 27, 2024 | Oct 03, 2019 | Series A | $65M | |
Mar 25, 2024 | Apr 17, 2012 | Series A | $10M | |
Feb 06, 2024 | - | - | - | |
Aug 10, 2023 | Jan 13, 2017 | Series B | $32.3M |
Team profile of Third Rock Ventures
Third Rock Ventures has a team of 94 membersÌýincluding 27 Partners, 28 Venture Partners and 8 PrincipalsÌýlocated in United States, Canada and . Third Rock Ventures' team does not sit on the board of any company as of now.Here is a list of top team members in Third Rock Ventures:
Name | Designation | Location | Board Memberships | Contact details |
---|---|---|---|---|
Partner | - | - | - | |
Partner | Boston | - | ||
Partner | Boston | - | ||
Partner | Framingham | - | ||
Partner | Boston | - | ||
Partner | Boston | - | ||
Partner | Boston | - | ||
Partner | Singapore | - | - | |
Partner | Waban | - | ||
Partner | - | - | - | |
Partner | Boston | - |
Co-investors of Third Rock Ventures
Over the past 17 years, 303 investors have co-invested in Third Rock Ventures's portfolio companies.
- Invested before Third Rock Ventures:ÌýHHS, and 15 others have invested in rounds before Third Rock Ventures. There are 3 companies where HHS has invested before Third Rock Ventures and 1 company where MPM Capital has invested before Third Rock Ventures.
- Top Co-investors of Third Rock Ventures:Ìý107 investors entered a company along with Third Rock Ventures. These include investors like Casdin Capital (7 companies).
- Invested after Third Rock Ventures:ÌýA total of 179 investors have invested in Third Rock Ventures's portfolio after their investments. Top Investors include Casdin Capital (18 companies), Wellington (10 companies) and Perceptive Advisors (9 companies).

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