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About Third Rock Ventures

Third Rock Ventures is a venture capital firm founded in 2007. It is primarily based out of Boston, United States. As of Dec 2024, Third Rock Ventures is an active investor, having invested in 70 companies, with 1 new investment in the last 12 months. It primarily invests in Series A round in United States based startups. Its investments are spread across a wide range of sectors from Life Sciences to High Tech and HealthTech. Most recently it led the $150M Series A round of Clasp Therapeutics along with Vivo Capital. This round also saw participation from Alexandria and other investors.
Overall, Third Rock Ventures portfolio has seen 22 IPOs and 19 acquisitions including key companies like Revolution Medicines, Rhythm Pharmaceuticals and Blueprint Medicines. A lot of funds co-invest with Third Rock Ventures, with names like Casdin Capital sharing a substantial percentage of its portfolio.
Third Rock Ventures has team of 94 people including 27 partners.
Key Metrics
Team Members
, &
Portfolio Count
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Series A, Series B &
Portfolio IPOs
Portfolio Acquisitions
Portfolio Soonicorns
Deals in last 12 months
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Third Rock Ventures' Investment Trends by Stage

Third Rock Ventures has made 55 investments in Series A stage, 7 investments in Series B stage, 3 investments in Series C stage and 1 investment in Series D stage.

Third Rock Ventures' Investment Trends by Sector

Third Rock Ventures has a diverse portfolio, with companies operating in the Life Sciences, High Tech, HealthTech, Healthcare and Enterprise Applications. Notably, it has invested in 68 Tech companies, 60 Enterprise (B2B) companies, 3 Tech hardware companies and at least 2 companies focusing on Software.
Here are Third Rock Ventures' investment trends by sector:
Note: We have considered here, only first round of investments
Breakdown of Third Rock Ventures' investments by sectorsLife Sciences (64)High Tech (18)
Sector
No. of Investments
Life Sciences
64
High Tech
18
HealthTech
4
Healthcare
3
Enterprise Applications
2
Others
5

Third Rock Ventures' Investment Trends by Geography

Third Rock Ventures has made most investments in United States (69), followed by Germany where it has made 1 investments.

Third Rock Ventures' recent investments

Third Rock Ventures has not made any investment in 2025 so far.
Here are the most recent investments by Third Rock Ventures:
Date
Company
Location
Round Details
Round Amount
Co-Investors
Dec 04, 2024
United States
Series D
$115M
Oct 18, 2024
United States
Series B
$225M
Aug 19, 2024
United States
Series D
$370M
Venrock [+17]
Apr 09, 2024
United States
Series A
$100M
Apr 03, 2024
United States
Series C
$55M
lockGet the detailed list of all investments by Third Rock Ventures. Download now!

IPOs and Publicly Listed companies in Third Rock Ventures' Portfolio

22 of Third Rock Ventures' portfolio companies have become public.ÌýMaze Therapeutics got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ), in Jan 2025 at marketcap of $700MÌýand Septerna got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ) at marketcap of $756M.
Here are Third Rock Ventures' portfolio companies that went public:
Company
IPO Date
First Invested on
First Round of Investment
Round Size
Jan 31, 2025
Mar 01, 2019
Series C
$191M
Oct 25, 2024
Jan 27, 2022
Series A
$100M
Jun 07, 2024
Mar 07, 2023
Series A
$100M
Nov 10, 2023
Feb 09, 2023
Series A
$200M
Sep 04, 2020
Mar 30, 2017
Series A
$55M

Acquired companies in Third Rock Ventures' Portfolio

19 companies from Third Rock Ventures' portfolio have been acquired.ÌýThe most recent acquisition were Bluebird Bio in Feb 2025Ìýby The Carlyle Group for $29M.
Here are Third Rock Ventures' portfolio companies that got acquired most recently:
Company
Acquisition Date
First Invested on
First Round of Investment
Round Size
Feb 21, 2025
Mar 12, 2010
Series B
$37.5M
Jun 27, 2024
Oct 03, 2019
Series A
$65M
Mar 25, 2024
Apr 17, 2012
Series A
$10M
Feb 06, 2024
-
-
-
Aug 10, 2023
Jan 13, 2017
Series B
$32.3M

Team profile of Third Rock Ventures

Third Rock Ventures has a team of 94 membersÌýincluding 27 Partners, 28 Venture Partners and 8 PrincipalsÌýlocated in United States, Canada and . Third Rock Ventures' team does not sit on the board of any company as of now.
Here is a list of top team members in Third Rock Ventures:
Name
Designation
Location
Board Memberships
Contact details
Partner
-
-
-
Partner
Boston
-
Partner
Boston
-
Partner
Framingham
-
Partner
Boston
-
Partner
Boston
-
Partner
Boston
-
Partner
Singapore
-
-
Partner
Waban
-
Partner
-
-
-
Partner
Boston
-
lockGet the full list of Third Rock Ventures' team & partners for free. Download now!

Co-investors of Third Rock Ventures

Over the past 17 years, 303 investors have co-invested in Third Rock Ventures's portfolio companies.

  • Invested before Third Rock Ventures:ÌýHHS, and 15 others have invested in rounds before Third Rock Ventures. There are 3 companies where HHS has invested before Third Rock Ventures and 1 company where MPM Capital has invested before Third Rock Ventures.
  • Top Co-investors of Third Rock Ventures:Ìý107 investors entered a company along with Third Rock Ventures. These include investors like Casdin Capital (7 companies).
  • Invested after Third Rock Ventures:ÌýA total of 179 investors have invested in Third Rock Ventures's portfolio after their investments. Top Investors include Casdin Capital (18 companies), Wellington (10 companies) and Perceptive Advisors (9 companies).
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Recent News related to Third Rock Ventures

•
Pharmaceutical Technology•Dec 04, 2024•Maze Therapeutics, Deep Track Capital, Frazier Life Sciences, Logos and 7 others
•
Fierce Biotech•Dec 03, 2024•Maze Therapeutics, Frazier Life Sciences, Deep Track Capital, Janus Henderson Investors and 4 others
•
Business Wire•Dec 03, 2024•Maze Therapeutics, Frazier Life Sciences, Deep Track Capital, Logos and 15 others
•
intelligence360•Nov 21, 2024•, Third Rock Ventures, Atlas Venture, Google Ventures and 1 other
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The Business Journals•Nov 12, 2024•Third Rock Ventures, Roche, Flare Therapeutics
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intelligence360•Oct 31, 2024•Seaport Therapeutics, General Atlantic, T. Rowe Price, Foresite Capital and 7 others
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Pharmaceutical Technology•Oct 21, 2024•Seaport Therapeutics, General Atlantic, T. Rowe Price, Foresite Capital and 10 others
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Pharmaceutical Technology•Sep 10, 2024•Candid Therapeutics, Venrock, VenBio, Foresite Capital and 3 others
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Business Wire•Sep 09, 2024•Candid, Venrock, Fairmont, TCG Crossover and 16 others
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