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About New Leaf Venture Partners

New Leaf Venture Partners is a venture capital firm founded in 2005. It is primarily based out of New York City, United States. As of Feb 2025, New Leaf Venture Partners is an active investor, having invested in 166 companies, with 1 new investment in the last 12 months. It primarily invests in Series C round in United States based startups. Its investments are spread across a wide range of sectors from Life Sciences to High Tech and HealthTech. Most recently it led the $15M Series E round of Truveris along with Canaan.
Overall, New Leaf Venture Partners portfolio has seen 1 unicorn, 29 IPOs and 77 acquisitions including key companies like CareDx, iRhythm Tech and Dynavax. A lot of funds co-invest with New Leaf Venture Partners, with names like Orbimed sharing a substantial percentage of its portfolio.
New Leaf Venture Partners has team of 11 people including 7 partners.
Key Metrics
Team Members
, &
Portfolio Count
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Series A, Series B &
Portfolio IPOs
Portfolio Acquisitions
Portfolio Unicorns
Portfolio Soonicorns
Deals in last 12 months
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New Leaf Venture Partners' Investment Trends by Stage

New Leaf Venture Partners has made 30 investments in Series A stage with an average round size of $27.4M, 28 investments in Series B stage with an average round size of $41.7M and 14 investments in Series C stage with an average round size of $40.7M.
Here are New Leaf Venture Partners' investment trends by stages:
Note: We have considered here, only first round of investments
Breakdown of New Leaf Venture Partners' investments by stage of entrySeries A (30)Series B (28)
Stage of entry
No. of Investments
Series A
30
Series B
28
Series C
14
Post IPO
7
Series D
5
Others
10

New Leaf Venture Partners' Investment Trends by Sector

New Leaf Venture Partners has a diverse portfolio, with companies operating in the Life Sciences, High Tech, HealthTech, Enterprise Applications and Sustainability Tech. Notably, it has invested in 150 Tech companies, 116 Enterprise (B2B) companies, 18 Saas companies and at least 17 companies focusing on Software.
Here are New Leaf Venture Partners' investment trends by sector:
Note: We have considered here, only first round of investments
Breakdown of New Leaf Venture Partners' investments by sectorsLife Sciences (76)High Tech (21)
Sector
No. of Investments
Life Sciences
76
High Tech
21
HealthTech
17
Enterprise Applications
13
Sustainability Tech
11
Others
32

New Leaf Venture Partners' Investment Trends by Geography

New Leaf Venture Partners has made most investments in United States (140), followed by United Kingdom where it has made 7 investments.
Here are New Leaf Venture Partners' investment trends by geography:
Note: We have considered here, only first round of investments
Breakdown of New Leaf Venture Partners' investments by countriesUnited States (78)United Kingdom (6)
Country
No. of Investments
United States
78
United Kingdom
6
Switzerland
3
Canada
2
Denmark
1
Others
4

New Leaf Venture Partners' recent investments

New Leaf Venture Partners has made 1 investments in 2025 so far - Abcuro.
Here are the most recent investments by New Leaf Venture Partners:
Date
Company
Location
Round Details
Round Amount
Co-Investors
Feb 07, 2025
United States
Series C
$200M
May 14, 2024
United States
Series E
$15M
May 03, 2024
Canada
Series C
$20M
Apr 11, 2024
United States
Series B
$24M
Canaan [+3]
Oct 23, 2023
United States
Post IPO
$100M
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Unicorns in New Leaf Venture Partners' Portfolio

New Leaf Venture Partners has 1 unicorns in its portfolio - Intarcia.ÌýThe most recent unicorn in their portfolio is Intarcia which became a unicorn in 2014, 7 years after New Leaf Venture Partners first invested in it.
Here is a list of unicorns in New Leaf Venture Partners' portfolio:
ÃØÃÜÑо¿Ëù Score
Company
Short Description
Founded year
Sector
Location
Company Stage
First Investment/ Acquisition Details
33
Provider of osmotic pump for subcutaneous drug delivery
1995
Boston
Series J
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IPOs and Publicly Listed companies in New Leaf Venture Partners' Portfolio

29 of New Leaf Venture Partners' portfolio companies have become public.ÌýRallybio got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ), in Jul 2021 at marketcap of $406MÌýand Edgewise Therapeutics got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ) at marketcap of $761M.
Here are New Leaf Venture Partners' portfolio companies that went public:
Company
IPO Date
First Invested on
First Round of Investment
Round Size
Jul 29, 2021
Apr 20, 2018
Series A
$37M
Mar 26, 2021
Sep 17, 2019
Series B
$50M
Feb 28, 2020
Feb 14, 2019
Series A
$116M
Feb 07, 2019
Jul 25, 2018
Series E
$133M
Sep 27, 2018
Oct 23, 2015
Series B
$41.6M

Acquired companies in New Leaf Venture Partners' Portfolio

77 companies from New Leaf Venture Partners' portfolio have been acquired.ÌýThe most recent acquisition were Chimerix in Mar 2025Ìýby Jazz Pharmaceuticals for $935M.
Here are New Leaf Venture Partners' portfolio companies that got acquired most recently:
Company
Acquisition Date
First Invested on
First Round of Investment
Round Size
Mar 05, 2025
Feb 14, 2011
Series F
$45M
Dec 30, 2024
-
-
-
May 29, 2024
May 26, 2021
Series D
$110M
Apr 29, 2024
Jul 13, 2016
Series B
$90.6M
Jan 08, 2024
Jun 06, 2017
Series B
$45M

Team profile of New Leaf Venture Partners

New Leaf Venture Partners has a team of 11 membersÌýincluding 7 Partners and 1 PrincipalÌýlocated in United States. New Leaf Venture Partners' team sits on the board of 1 company.
Here is a list of top team members in New Leaf Venture Partners:
Name
Designation
Location
Board Memberships
Contact details
Partner
Menlo Park
-
Partner
United States
-
Partner
New York City
Partner
New York City
-
Partner
New York City
-
Partner
Portsmouth
-
-
Partner
United States
-
-
Principal
New York City
-
-
Advisor
-
-
-
Advisor
Palo Alto
-
Associate
Menlo Park
-
-
lockGet the full list of New Leaf Venture Partners' team & partners for free. Download now!

Co-investors of New Leaf Venture Partners

Over the past 20 years, 642 investors have co-invested in New Leaf Venture Partners's portfolio companies.

  • Invested before New Leaf Venture Partners:ÌýOrbimed, HHS and 245 others have invested in rounds before New Leaf Venture Partners. There are 6 companies where Orbimed has invested before New Leaf Venture Partners and 5 companies where HHS has invested before New Leaf Venture Partners.
  • Top Co-investors of New Leaf Venture Partners:Ìý208 investors entered a company along with New Leaf Venture Partners. These include investors like Orbimed (9 companies).
  • Invested after New Leaf Venture Partners:ÌýA total of 187 investors have invested in New Leaf Venture Partners's portfolio after their investments. Top Investors include RA Capital Management (5 companies), SVB (5 companies) and Redmile Group (4 companies).
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Recent News related to New Leaf Venture Partners

•
intelligence360•Feb 19, 2025•Abcuro, Soleus Capital, , BlackRock and 11 others
•
intelligence360•Oct 02, 2024•, New Leaf Venture Partners, Longitude Capital, Tekla Capital Management and 2 others
•
Pulse 2.0•May 28, 2024•Truveris, Canaan, New Leaf Venture Partners
•
Business Wire•May 14, 2024•Truveris, Canaan, New Leaf Venture Partners
•
Healio•May 07, 2024•Qlaris Bio, Canaan, New Leaf Venture Partners, abrdn and 2 others
•
Business Wire•Mar 19, 2024•Flosonics Medical, New Leaf Venture Partners, Arboretum Ventures, Genesys Capital and 1 other
•
Webrazzi•Sep 06, 2023•STAR Therapeutics, Orbimed, Sofinnova Investments, Qatar Investment Authority and 14 others
•
Business Wire•Aug 17, 2023•Abcuro, Redmile Group, Bain Capital Life Sciences, RA Capital Management and 11 others
•
GeekWire•Aug 08, 2023•Windup Minds, The Venture Reality Fund, Acequia Capital, New Leaf Ventures and 1 other
•
WebDisclosure•Mar 28, 2023•Harpoon Therapeutics, New Leaf Venture Partners, Arix Bioscience, Invus and 2 others
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