About New Leaf Venture Partners
New Leaf Venture Partners is a venture capital firm founded in 2005. It is primarily based out of New York City, United States. As of Feb 2025, New Leaf Venture Partners is an active investor, having invested in 166 companies, with 1 new investment in the last 12 months. It primarily invests in Series C round in United States based startups. Its investments are spread across a wide range of sectors from Life Sciences to High Tech and HealthTech. Most recently it led the $15M Series E round of Truveris along with Canaan.
Overall, New Leaf Venture Partners portfolio has seen 1 unicorn, 29 IPOs and 77 acquisitions including key companies like CareDx, iRhythm Tech and Dynavax. A lot of funds co-invest with New Leaf Venture Partners, with names like Orbimed sharing a substantial percentage of its portfolio.
New Leaf Venture Partners has team of 11 people including 7 partners.
Key Metrics
Team Members
, &
Portfolio Count
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Series A, Series B &
Portfolio IPOs
Portfolio Acquisitions
Portfolio Unicorns
Portfolio Soonicorns
Deals in last 12 months
New Leaf Venture Partners' Year-on-Year Investment Trends
New Leaf Venture Partners has invested in 166 companies over the last 20 years, with an average of 4 new investments annually in the last 10 years. In 2024, it made 3 investments, while as of Feb 2025, it has made 1 investment in this year. Its most recent first time investment was in Flosonics Medical and most recent follow-on round was in Abcuro.
Year | No. of Investments | ||
---|---|---|---|
1stÌý¸é´Ç³Ü²Ô»å | Follow-on | Total | |
2025 (YTD) | 0 | 1 | 1 |
2024 | 1 | 2 | 3 |
2023 | 2 | 3 | 5 |
2022 | 2 | 3 | 5 |
2021 | 3 | 2 | 5 |
2020 | 4 | 5 | 9 |
2019 | 7 | 3 | 10 |
2018 | 9 | 3 | 12 |
2017 | 3 | 4 | 7 |
2016 | 5 | 0 | 5 |

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New Leaf Venture Partners' Investment Trends by Stage
New Leaf Venture Partners has made 30 investments in Series A stage with an average round size of $27.4M, 28 investments in Series B stage with an average round size of $41.7M and 14 investments in Series C stage with an average round size of $40.7M.Note: We have considered here, only first round of investments
Stage of entry | No. of Investments |
---|---|
Series A | 30 |
Series B | 28 |
Series C | 14 |
Post IPO | 7 |
Series D | 5 |
Others | 10 |
New Leaf Venture Partners' Investment Trends by Sector
New Leaf Venture Partners has a diverse portfolio, with companies operating in the Life Sciences, High Tech, HealthTech, Enterprise Applications and Sustainability Tech. Notably, it has invested in 150 Tech companies, 116 Enterprise (B2B) companies, 18 Saas companies and at least 17 companies focusing on Software.
Note: We have considered here, only first round of investments
Sector | No. of Investments |
---|---|
Life Sciences | 76 |
High Tech | 21 |
HealthTech | 17 |
Enterprise Applications | 13 |
Sustainability Tech | 11 |
Others | 32 |
New Leaf Venture Partners' Investment Trends by Geography
New Leaf Venture Partners has made most investments in United States (140), followed by United Kingdom where it has made 7 investments.
Note: We have considered here, only first round of investments
Country | No. of Investments |
---|---|
United States | 78 |
United Kingdom | 6 |
Switzerland | 3 |
Canada | 2 |
Denmark | 1 |
Others | 4 |
New Leaf Venture Partners' recent investments
Here are the most recent investments by New Leaf Venture Partners:
Date | Company | Location | Round Details | Round Amount | Co-Investors |
---|---|---|---|---|---|
Feb 07, 2025 | United States | Series C | $200M | ||
May 14, 2024 | United States | Series E | $15M | ||
May 03, 2024 | Canada | Series C | $20M | Arboretum Ventures [+2] | |
Apr 11, 2024 | United States | Series B | $24M | Canaan [+3] | |
Oct 23, 2023 | United States | Post IPO | $100M | Soleus Capital [+8] |
Unicorns in New Leaf Venture Partners' Portfolio
Here is a list of unicorns in New Leaf Venture Partners' portfolio:
ÃØÃÜÑо¿Ëù Score | Company | Short Description | Founded year | Sector | Location | Company Stage | First Investment/ Acquisition Details |
---|---|---|---|---|---|---|---|
33 | Provider of osmotic pump for subcutaneous drug delivery | 1995 | Boston | Series J | yjtksip |
IPOs and Publicly Listed companies in New Leaf Venture Partners' Portfolio
Here are New Leaf Venture Partners' portfolio companies that went public:
Company | IPO Date | First Invested on | First Round of Investment | Round Size |
---|---|---|---|---|
Jul 29, 2021 | Apr 20, 2018 | Series A | $37M | |
Mar 26, 2021 | Sep 17, 2019 | Series B | $50M | |
Feb 28, 2020 | Feb 14, 2019 | Series A | $116M | |
Feb 07, 2019 | Jul 25, 2018 | Series E | $133M | |
Sep 27, 2018 | Oct 23, 2015 | Series B | $41.6M |
Acquired companies in New Leaf Venture Partners' Portfolio
Here are New Leaf Venture Partners' portfolio companies that got acquired most recently:
Company | Acquisition Date | First Invested on | First Round of Investment | Round Size |
---|---|---|---|---|
Mar 05, 2025 | Feb 14, 2011 | Series F | $45M | |
Dec 30, 2024 | - | - | - | |
May 29, 2024 | May 26, 2021 | Series D | $110M | |
Apr 29, 2024 | Jul 13, 2016 | Series B | $90.6M | |
Jan 08, 2024 | Jun 06, 2017 | Series B | $45M |
Team profile of New Leaf Venture Partners
New Leaf Venture Partners has a team of 11 membersÌýincluding 7 Partners and 1 PrincipalÌýlocated in United States. New Leaf Venture Partners' team sits on the board of 1 company.Here is a list of top team members in New Leaf Venture Partners:
Name | Designation | Location | Board Memberships | Contact details |
---|---|---|---|---|
Partner | Menlo Park | - | ||
Partner | United States | - | ||
Partner | New York City | |||
Partner | New York City | - | ||
Partner | New York City | - | ||
Partner | Portsmouth | - | - | |
Partner | United States | - | - | |
Principal | New York City | - | - | |
Advisor | - | - | - | |
Advisor | Palo Alto | - | ||
Associate | Menlo Park | - | - |
Co-investors of New Leaf Venture Partners
Over the past 20 years, 642 investors have co-invested in New Leaf Venture Partners's portfolio companies.
- Invested before New Leaf Venture Partners:ÌýOrbimed, HHS and 245 others have invested in rounds before New Leaf Venture Partners. There are 6 companies where Orbimed has invested before New Leaf Venture Partners and 5 companies where HHS has invested before New Leaf Venture Partners.
- Top Co-investors of New Leaf Venture Partners:Ìý208 investors entered a company along with New Leaf Venture Partners. These include investors like Orbimed (9 companies).
- Invested after New Leaf Venture Partners:ÌýA total of 187 investors have invested in New Leaf Venture Partners's portfolio after their investments. Top Investors include RA Capital Management (5 companies), SVB (5 companies) and Redmile Group (4 companies).

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Recent News related to New Leaf Venture Partners
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intelligence360•Oct 02, 2024•, New Leaf Venture Partners, Longitude Capital, Tekla Capital Management and 2 others
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Business Wire•Mar 19, 2024•Flosonics Medical, New Leaf Venture Partners, Arboretum Ventures, Genesys Capital and 1 other
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Webrazzi•Sep 06, 2023•STAR Therapeutics, Orbimed, Sofinnova Investments, Qatar Investment Authority and 14 others
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Business Wire•Aug 17, 2023•Abcuro, Redmile Group, Bain Capital Life Sciences, RA Capital Management and 11 others
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WebDisclosure•Mar 28, 2023•Harpoon Therapeutics, New Leaf Venture Partners, Arix Bioscience, Invus and 2 others