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About Omega Funds

Omega Funds is a venture capital firm founded in 2004. It is primarily based out of Boston, United States. As of May 2025, Omega Funds is an active investor, having invested in 135 companies, with 8 new investments in the last 12 months. It primarily invests in Series B round in United States based startups. Its investments are spread across a wide range of sectors from Life Sciences to High Tech and Enterprise Applications. Most recently it led the Undisclosed Seed round of Ousia Pharma.
Overall, Omega Funds portfolio has seen 1 unicorn, 45 IPOs and 44 acquisitions including key companies like BridgeBio, Evotec and Juno Therapeutics. A lot of funds co-invest with Omega Funds, with names like EcoR1 sharing a substantial percentage of its portfolio.
Omega Funds has team of 26 people including 13 partners.
Key Metrics
Team Members
, &
Portfolio Count
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Series A, Series B &
Portfolio Acquisitions
Portfolio Unicorns
Portfolio Soonicorns
Deals in last 12 months

Omega Funds' List of Top Investments

Omega Funds has a portfolio of 135 companies, one of which is a Unicorn. Their most notable investments are in Chord Therapeutics and JenaValve Technology.Their portfolio spans across United States, United Kingdom, GermanyÌý²¹²Ô»å 15 more locations. They have invested in Life Sciences, High Tech, Enterprise ApplicationsÌý²¹²Ô»å 13 other sectors, across stages such as Series A, Series B Ìý²¹²Ô»å 4 more. Here is the list of top investments by Omega Funds:
Developer of therapeutics for the treatment of genetic diseases. It utilizes a mapping of various genetic disease landscapes to identify opportunities for therapeutic intervention. The company's drug candidates include PTCH1-inhibitor for Gorlin syndrome and S1P-lyase inhibitor for Darier disease and Hailey-Hailey disease and others.

Key facts about BridgeBio

Key facts about Evotec

  • Founded Year: 1993
  • Location: Hamburg (Germany)
  • Stage: Public
  • Total Funding till date: $25M
  • Employee Count: 252 as on Dec 31, 2020
  • Investors: Omega Funds, Eiffel Investment Group and 20 Others
  • Latest Funding Round: Grant (prize money), Jun 02, 2023, $1.7M
  • Highlight: Public
Juno Therapeutics is developing T cell-based cancer immunotherapies based on chimeric antigen receptor and high-affinity T cell receptor technologies to genetically engineer T cells to recognize and kill cancer cells. Company's lead therapies are for the treatment of acute lymphoblastic leukemia and adult B-cell malignancies. Other programs in development are for the treatment of acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL), non-Hodgkin’s lymphoma (NHL) and non-small cell lung cancer (NSCLC).

Key facts about Juno Therapeutics

  • Founded Year: 2013
  • Location: Seattle (United States)
  • Annual Revenue: $112M as on Dec 31, 2017
  • Stage: Acquired
  • Total Funding till date: $317M
  • Employee Count: 520 as on Dec 31, 2017
  • Investors: Ridgeback Capital Management, BB Biotech and 14 Others
  • Latest Funding Round: Post IPO, Oct 05, 2017, $31.1M
  • Highlight: Acquired
Developer of cell-based therapies for cancer treatment. The company has developed its proprietary synthetic biology platform to produce cell and gene therapies for cancer treatment. It allows engineering and designing of optimized therapeutic gene circuits for various therapeutic applications. It offers CAR-NK-based therapies for multiple cancer and tumors.

Key facts about Senti Biosciences

5.

Developer of drugs based on T-cell receptor technology for the treatment of cancer. The company's proprietary technology is focused on small protein molecules called ImmTACs (Immune mobilizing monoclonal TCRs Against Cancer) that enable the immune system to recognize and kill cancerous or bacterially/virally infected cells. They enable this by recognizing peptide-HLA complexes on the surface of cancer cells and effecting a potent and specific T cell response to destroy cancer cells (through an anti-CD3 antibody fragment). Its lead candidate is IMCgp100, a novel bi-specific immunotherapeutic, which is used for the treatment of uveal melanoma.

Key facts about Immunocore

  • Founded Year: 2008
  • Location: Abingdon (United Kingdom)
  • Annual Revenue: £179M as on Dec 31, 2022
  • Stage: Public
  • Total Funding till date: $601M
  • Employee Count: 293 as on Jan 31, 2022
  • Investors: NeoMed, Rock Springs Capital and
  • Latest Funding Round: Post IPO, Jul 18, 2022, $140M
  • Highlight: Public
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Omega Funds' Investments by Stage

Omega Funds has made 28 investments in Series A stage with an average round size of $77.5M, 25 investments in Series B stage with an average round size of $81M and 14 investments in Series C stage with an average round size of $96.5M.
Here are Omega Funds' investments by stage:
Note: We have considered here, only first round of investments
Breakdown of Omega Funds' investments by stage of entrySeries A (28)Series B (25)
Stage of entry
No. of Investments
Series A
28
Series B
25
Series C
14
Post IPO
7
Seed
4
Others
4

Omega Funds' Investments by Sector

Omega Funds has a diverse portfolio, with companies operating in the Life Sciences, High Tech, Sustainability Tech, Enterprise Applications and Healthcare. Notably, it has invested in 113 Enterprise (B2B) companies, 112 Tech companies, 11 Tech hardware companies and at least 9 companies focusing on Software.
Here are Omega Funds' investments by sector:
Note: We have considered here, only first round of investments
Breakdown of Omega Funds' investments by sectorsLife Sciences (79)High Tech (15)
Sector
No. of Investments
Life Sciences
79
High Tech
15
Sustainability Tech
8
Enterprise Applications
4
Healthcare
4
Others
4

Omega Funds' Investments by Geography

Omega Funds has made most investments in United States (58), followed by Switzerland where it has made 7 investments.
Here are Omega Funds' investments by geography:
Note: We have considered here, only first round of investments
Breakdown of Omega Funds' investments by countriesUnited States (58)Switzerland (7)
Country
No. of Investments
United States
58
Switzerland
7
United Kingdom
6
Canada
2
Denmark
2
Others
8

Omega Funds' recent investments

Omega Funds has made 2 investments in 2025 so far - Ousia Pharma and Callio Therapeutics.
Here are the most recent investments by Omega Funds:
Date
Company
Location
Round Details
Round Amount
Co-Investors
May 06, 2025
Denmark
Seed
Undisclosed
-
Mar 03, 2025
United States
Series A
$187M
Dec 19, 2024
United States
Series C
$90.8M
[+6]
Dec 17, 2024
United States
Series C
$208M
Nov 13, 2024
United States
Series E
$60M
[+6]
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Unicorns in Omega Funds' Portfolio

Omega Funds has 1 unicorns in its portfolio - Intarcia.ÌýThe most recent unicorn in their portfolio is Intarcia which became a unicorn in 2014, -11 years after Omega Funds first invested in it.
Here is a list of unicorns in Omega Funds' portfolio:
ÃØÃÜÑо¿Ëù Score
Company
Short Description
Founded year
Sector
Location
Company Stage
First Investment/ Acquisition Details
33
Provider of osmotic pump for subcutaneous drug delivery
1995
Boston
Series J
dladcdr

IPOs and Publicly Listed companies in Omega Funds' Portfolio

45 of Omega Funds' portfolio companies have become public.ÌýKestra Medical Technologies got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ), in Mar 2025 at marketcap of $842MÌý²¹²Ô»å Beta Bionics got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ) at marketcap of $695M.
Here are Omega Funds' portfolio companies that went public:
Company
IPO Date
First Invested on
First Round of Investment
Round Size
Mar 06, 2025
Jul 24, 2024
Series B
$196M
Jan 30, 2025
Aug 28, 2023
Series D
$100M
Oct 11, 2024
Jun 02, 2022
Series A
$200M
Sep 13, 2024
Mar 06, 2023
Series B
$108M
Jun 28, 2024
Mar 07, 2024
Series C
$259M

Acquired companies in Omega Funds' Portfolio

44 companies from Omega Funds' portfolio have been acquired.ÌýThe most recent acquisition were Kronos Bio in May 2025Ìýby Concentra Biosciences.
Here are Omega Funds' portfolio companies that got acquired most recently:
Company
Acquisition Date
First Invested on
First Round of Investment
Round Size
May 01, 2025
Aug 24, 2020
Series B
$148M
Mar 03, 2025
Jan 09, 2023
Series C
$60M
Jul 25, 2024
Jul 19, 2013
Series C
$73.4M
Jul 08, 2024
Jun 30, 2016
Series A
$51.5M
May 30, 2024
Nov 14, 2023
Series A
$65M

Team profile of Omega Funds

Omega Funds has a team of 26 membersÌýincluding 13 Partners, 3 Venture Partners and 3 PrincipalsÌýlocated in United States, Switzerland and . Omega Funds' team does not sit on the board of any company as of now.
Here is a list of top team members in Omega Funds:
Name
Designation
Location
Board Memberships
Contact details
Partner
Boston
-
Partner
Geneva
-
Partner
Geneva
-
Partner
Boston
-
Partner
United States
-
-
Partner
Lexington
-
-
Partner
Switzerland
-
Partner
Toronto
-
Partner
Boston
-
Partner
Cambridge
-
-
Partner
Cambridge
-
-
lockGet the full list of Omega Funds' team & partners for free. Download now!

Co-investors of Omega Funds

Over the past 19 years, 562 investors have co-invested in Omega Funds's portfolio companies.

  • Invested before Omega Funds:ÌýHHS, Atlas Venture and 191 others have invested in rounds before Omega Funds. There are 7 companies where HHS has invested before Omega Funds and 6 companies where Atlas Venture has invested before Omega Funds.
  • Top Co-investors of Omega Funds:Ìý215 investors entered a company along with Omega Funds. These include investors like EcoR1 (8 companies).
  • Invested after Omega Funds:ÌýA total of 154 investors have invested in Omega Funds's portfolio after their investments. Top Investors include Alexandria (5 companies), Bain Capital Life Sciences (4 companies) and Invus (4 companies).
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Recent News related to Omega Funds

•
Pulse 2.0•Jun 17, 2025•, Omega Funds, Atlas Venture, Lightspeed Venture Partners and 7 others
•
PR Newswire•May 06, 2025•Ousia Pharma, Omega Funds
•
PR Newswire•May 06, 2025•Ousia Pharma, Omega Funds
•
intelligence360•Mar 17, 2025•Callio Therapeutics, Frazier Life Sciences, Jeito, Novo Holdings and 7 others
•
Pharmaceutical Technology•Mar 04, 2025•Callio Therapeutics, Frazier Life Sciences, Jeito, Omega Funds and 3 others
•
Jinglingshuju•Mar 04, 2025•Callio Therapeutics, Frazier Life Sciences, Jeito, Novo Holdings and 6 others
•
BioPharmaDive•Mar 03, 2025•Hummingbird Bioscience, Frazier Healthcare Partners, Jeito, Novo Holdings and 9 others
•
GlobeNewswire•Mar 03, 2025•Jeito, Callio Therapeutics, Hummingbird Bioscience, Frazier Life Sciences and 8 others
•
CNW•Mar 03, 2025•Callio Therapeutics, Frazier Life Sciences, Jeito, Novo Holdings and 10 others
•
intelligence360•Jan 17, 2025•Aviceda Therapeutics, Omega Funds, TCG Crossover, Enavate Sciences and 3 others

FAQ's about Omega Funds

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