About Osage Partners
Osage Partners is a venture capital firm founded in 1990. It is primarily based out of Philadelphia, United States. As of Oct 2022, Osage Partners has invested in 39 companies. It primarily invests in Series A round in United States based startups. Its investments are spread across a wide range of sectors from Life Sciences to Enterprise Applications and High Tech. Most recently it led the $65.4M Series D round of SiFive along with Qualcomm Ventures. This round also saw participation from Spark Capital and other investors.
Overall, Osage Partners portfolio has seen 2 unicorns, 5 IPOs and 15 acquisitions including key companies like Guardant Health, Spero Therapeutics and SiFive. A lot of funds co-invest with Osage Partners, with names like Correlation Ventures sharing a substantial percentage of its portfolio.
Key Metrics
Portfolio Count
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Series A, Seed &
Portfolio IPOs
Cyteir, &
Portfolio Acquisitions
Portfolio Unicorns
Portfolio Soonicorns
Osage Partners' Year-on-Year Investment Trends
Osage Partners has invested in 39 companies over the last 18 years, with an average of 1 new investment annually in the last 10 years. Its most recent first time investment was in Connectbase and most recent follow-on round was in .
Year | No. of Investments | ||
---|---|---|---|
1stÌý¸é´Ç³Ü²Ô»å | Follow-on | Total | |
2025 (YTD) | 0 | 0 | 0 |
2024 | 0 | 0 | 0 |
2023 | 0 | 0 | 0 |
2022 | 1 | 0 | 1 |
2021 | 0 | 0 | 0 |
2020 | 0 | 0 | 0 |
2019 | 1 | 0 | 1 |
2018 | 2 | 0 | 2 |
2017 | 0 | 1 | 1 |
2016 | 1 | 0 | 1 |

Get Osage Partners' portfolio delivered to your inbox!
Osage Partners' Investment Trends by Stage
Osage Partners has made 9 investments in Series A stage with an average round size of $15M, 4 investments in Seed stage with an average round size of $3.34M and 3 investments in Series C stage with an average round size of $35.2M.Note: We have considered here, only first round of investments
Stage of entry | No. of Investments |
---|---|
Series A | 9 |
Seed | 4 |
Series C | 3 |
Series B | 2 |
Series D | 2 |
Others | 1 |
Osage Partners' Investment Trends by Sector
Osage Partners has a diverse portfolio, with companies operating in the Enterprise Applications, Life Sciences, High Tech, Vertical SaaS and Consumer. Notably, it has invested in 29 Tech companies, 25 Enterprise (B2B) companies, 8 Software companies and at least 6 companies focusing on Saas.
Note: We have considered here, only first round of investments
Sector | No. of Investments |
---|---|
Enterprise Applications | 6 |
Life Sciences | 6 |
High Tech | 4 |
Vertical SaaS | 3 |
Consumer | 2 |
Others | 12 |
Osage Partners' Investment Trends by Geography
Osage Partners has made most investments in United States (35).
Osage Partners' recent investments
Here are the most recent investments by Osage Partners:
Date | Company | Location | Round Details | Round Amount | Co-Investors |
---|---|---|---|---|---|
Oct 12, 2022 | United States | Series C | $22M | [+3] | |
Jun 06, 2019 | United States | Series D | $65.4M | [+4] | |
Jan 17, 2018 | United States | Series J | $8M | [+1] | |
Jan 11, 2018 | United States | Seed | $2.7M | [+1] | |
May 12, 2017 | United States | Series C | $11M | [+2] |
Unicorns in Osage Partners' Portfolio
Here is a list of unicorns in Osage Partners' portfolio:
ÃØÃÜÑо¿Ëù Score | Company | Short Description | Founded year | Sector | Location | Company Stage | First Investment/ Acquisition Details |
---|---|---|---|---|---|---|---|
62 | Provider of AI-based IP cores for system-on-chips | 2015 | San Mateo | Series F | sawpvyb | ||
33 | Provider of osmotic pump for subcutaneous drug delivery | 1995 | Boston | Series J | qgmxss{ |
IPOs and Publicly Listed companies in Osage Partners' Portfolio
Here are Osage Partners' portfolio companies that went public:
Company | IPO Date | First Invested on | First Round of Investment | Round Size |
---|---|---|---|---|
Jun 18, 2021 | - | - | - | |
Nov 29, 2018 | - | - | - | |
Oct 04, 2018 | - | - | - | |
Nov 02, 2017 | - | - | - | |
Feb 09, 2011 | Aug 21, 2009 | Series D | $40M |
Acquired companies in Osage Partners' Portfolio
Here are Osage Partners' portfolio companies that got acquired most recently:
Company | Acquisition Date | First Invested on | First Round of Investment | Round Size |
---|---|---|---|---|
Aug 26, 2024 | Apr 22, 2015 | Seed | $885K | |
Oct 24, 2022 | - | - | - | |
Aug 23, 2021 | - | - | - | |
Aug 17, 2021 | - | - | - | |
Jul 27, 2021 | - | - | - |
Co-investors of Osage Partners
Over the past 18 years, 149 investors have co-invested in Osage Partners's portfolio companies.
- Invested before Osage Partners:Ìý, Alta Partners and 58 others have invested in rounds before Osage Partners. There are 2 companies where osti.gov has invested before Osage Partners and 2 companies where Alta Partners has invested before Osage Partners.
- Top Co-investors of Osage Partners:Ìý52 investors entered a company along with Osage Partners. These include investors like Correlation Ventures (2 companies).
- Invested after Osage Partners:ÌýA total of 37 investors have invested in Osage Partners's portfolio after their investments. Top Investors include Samsung Venture Investment (2 companies), Osage Venture Partners (2 companies) and Coatue (1 company).

Get full list of Osage Partners' co-investors delivered to your inbox!
Recent News related to Osage Partners
•
•
•
BioWorld•Jan 13, 2025•Normunity, Samsara BioCapital, Enavate Sciences, Regeneron Ventures and 9 others
•
•
Business Wire•Aug 29, 2023•TruLite Health, Osage Venture Partners, Xcellerant Ventures, Ensemble Innovation Ventures and 1 other
•
vcbay.news•Apr 28, 2023•DeepHow, LG Technology Ventures, Owl Ventures, Sierra Ventures and 4 others
•
vcbay.news•Mar 10, 2023•FOUNT, Osage Venture Partners, Grotech Ventures, Lavrock Ventures and 2 others
•
PR Newswire•Nov 14, 2022•Curavit, Osage Venture Partners, Royal Street Ventures, Narrow Gauge Ventures and 2 others
•
FinSMEs•Feb 09, 2022•DeepSurface, Differential Ventures, Osage Partners, Ginossar Ventures and 1 other
•
MarTech Series•Nov 16, 2021•Circonus, Baird Capital, NewSpring, Osage Venture Partners and 2 others